Cerebral amyloid angiopathy with symptomatic or occult subarachnoid haemorrhage.
نویسندگان
چکیده
araiosis ( fig. 1 ). Routine blood tests including markers for vasculitis and coagulopathy were negative. A drug abuse screen was negative. A four-vessel digital subtraction angiogram was normal. A brain and dura biopsy of the right frontal lobe was performed to exclude primary CNS vasculitis. The biopsy showed hyaline thickening of the walls of mediumand small-sized arteries and arterioles in the meninges, with apple-green birefringence on Congo red staining ( fig. 2 ). The patient was diagnosed with clinically probable CAA with supporting pathology [5] . She was readmitted 8 weeks later with a recurrent acute SAH as evidenced by acute headache and subarachnoid blood on CT over the left parietal area. This was managed conservatively and on review 12 months later she remains well.
منابع مشابه
Subarachnoid haemorrhage in the elderly: a necropsy study of the association with cerebral amyloid angiopathy.
To clarify the contribution of cerebral amyloid angiopathy (CAA) to subarachnoid haemorrhage (SAH) in the elderly, relationships between SAH and CAA were investigated in 997 necropsy cases aged 60 years or older. Primary SAH (bleeding from subarachnoid vessels) was found in 15 cases (1.5%). There was no case in which primary SAH was clearly attributed to CAA. Secondary SAH [secondary rupture of...
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عنوان ژورنال:
- European neurology
دوره 57 2 شماره
صفحات -
تاریخ انتشار 2007